Eduardo V. Zambrano
(IPMB 1994)
Positions held since graduation:
CERTIFICATIONS
Educational Commission for Foreign Medical Graduates (ECFMG), 1997
Anatomic and Clinical Pathology, American Board of Pathology, 2003
Pediatric Pathology, American Board of Pathology, 2003
RESIDENCY AND FELLOWSHIP TRAINING:
Clinical Fellow in Pediatric Pathology, Boston Children’s Hospital, Harvard Medical School. Boston, MA (July 2002 – June 2003)
Comined Anatomic and Clinical Pathology Residency Programs (AP/CP), Departments of Pathology and Laboratory Medicine, Yale-New Haven Hospital, Yale University School of Medicine. New Haven, CT (July 1997 - June 2002)
PROFESSIONAL EXPERIENCE:
Academic Appointments:
Associate Professor, Department of Pathology, Medical College of Wisconsin. Milwaukee, WI (since January 1, 2010)
Associate Professor, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2009 – December 31, 2009)
Assistant Professor, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2004 - June 30, 2009)
Instructor, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2003 - June 30, 2004)
Professor, School of Medicine, Universidad Católica de Santiago de Guayaquil. Guayaquil, Ecuador (since 1996)
Clinical Experience:
Consultant, Musculoskeletal Pathology, Department of Pathology, Yale University School of Medicine. New Haven, CT (January 2007 – December 2009)
Attending Pathologist, Department of Pathology, Milford Hospital. Milford, CT (May 1, 2008 – December 31, 2009)
Attending Pathologist, Department of Pathology, Yale-New Haven Hospital. New Haven, CT (July 1, 2003 – December 31, 2009)
Attending Pathologist, Department of Pathology, Bridgeport Hospital. Bridgeport, CT (July 1, 2003 – December 31, 2009)
Teaching Experience:
Lecturer, Bone and Soft Tissue Pathology, second-year medical students, Medical College of Wisconsin. Milwaukee, WI (since January 2010)
Lecturer, Pediatric Pathology Overview and Developmental Disorders of the Musculoskeletal System.General Principles of Pathology Course for first-year medical students, Yale University School of Medicine (2008-2009)
Director, Pathology labs and lectures. Cardiovascular Module, Mechanism of Disease Course, Yale University School of Medicine. New Haven, CT (2006-2009)
Lecturer, Pathology of Pediatric Solid Tumors. Seminar series for Pediatric Oncology Attendings, Fellows and Advanced Practitioners, Department of Pediatrics, Yale University School of Medicine (2008-2009)
Co-leader, Pathology Course Tutorials for second-year medical students, Yale University School of Medicine (2003-2007)
Lecturer, Cardiovascular Pathology. Pathology Lecture series for first-year students, Physician Associate Program, Yale University School of Medicine (2003-2009)
Head Professor of Biology, Faculty of Medical Sciences, Universidad Católica de Santiago de Guayaquil (UCSG) (March 1996 – June 1997)
Visiting Professor of Biology, Faculty of Medical Sciences, Universidad Católica de Santiago de Guayaquil (UCSG) (March 1995 - March 1996)
Invited Professor of Biology. Undergraduate Faculty of Medical Sciences. Universidad Católica de Santiago de Guayaquil (UCSG) (July - September 1993)
Administrative Experience:
Director, Surgical Pathology, Department of Pathology, Medical College of Wisconsin. Milwaukee, WI (since January 1, 2010)
Director, Musculoskeletal Pathology Service, Department of Pathology, Medical College of Wisconsin. Milwaukee, WI (since January 1, 2010)
Director, Orthopaedic Pathology, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2009 – December 31, 2009)
Director, Pediatric and Developmental Pathology, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2008 – December 31, 2009)
Associate Director, Anatomic Pathology Residency Program, Department of Pathology, Yale University School of Medicine. New Haven, CT (November 2008 – November 2009)
Assistant Director, Autopsy Service, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2007 – December 31, 2009)
Secretary/ Treasurer, Latin American Pathology Foundation (LAPF) (March 2006 – March 2009) and Manager of the LAPF website (since February 2008)
Member,Residency Selection Committee, Department of Pathology, Yale-New Haven Hospital, Yale University School of Medicine. New Haven, CT (2004-2005, 2006-2007 and 2008-2009)
Administrative Chief Resident, Department of Pathology, Yale-New Haven Hospital, Yale University School of Medicine. New Haven, CT (July 2001 - June 2002)
Inspector (# 705549), for the College of American Pathologists (May 2001 and September 2004)
Acting Director, Instituto de Biología Molecular Tropical [Institute of Tropical Molecular Biology] (IBMT), Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (August 1995 - May 1997)
Editorial Experience:
Member, Editorial Board, Annals of Diagnostic Pathology (since January 2010)
Member, Scientific Committee, X Virtual Hispanic-American Anatomical Pathology Meeting (2009)
Member, Editorial Board, Pediatric and Developmental Pathology [official Journal of the Society for Pediatric Pathology, ISSN 1093-5266 (printed version), ISSN 1615-5742 (electronic version)] (March, 2004-June, 2007)
Reviewer, Pediatric and Developmental Pathology (2000-2004)
Reviewer, Journal of Medical Case Reports (2008)
Reviewer, Histology and Histopathology (2009)
SOCIETY MEMBERSHIPS:
Fellow, College of American Pathologists (CAP)
Member, American Medical Association (AMA)
Member, United States and Canadian Academy of Pathology (USCAP)
Member, Society for Pediatric Pathology (SPP)
Member, Nominating Committee, Society for Pediatric Pathology (2005-2008)
Member, International Society of Bone and Soft Tissue Pathology (ISBSTP)
Member, Arkadi M. Rywlin International Pathology Club
Member, American Diabetes Association
Associate Member, Endocrine Pathology Society (EPS)
Member, Children’s Hospital Boston Alumni Association
Active Member and former Chair of Members Committee, Latin American Pathology Foundation (LAPF)
Founding Member, Dr. Roberto Gilbert Elizalde Foundation, a foundation for the advancement and development of molecular biology in Guayaquil, Ecuador
Associate Member, Colegio Ecuatoriano de Cirujanos [Ecuadorian College of Surgeons]
Active Member, Sociedad Ecuatoriana de Colo-Proctología [Ecuadorian Society of Colo-Proctology]
Former member, Board of Directors, Hispanos Unidos, a foundation for support and community programs for the Hispanic population with AIDS and other diseases, based in New Haven, CT (October 2000 - October 2001)
Projects involved in:
ELGAN (Extremely Low Gestational Age Newborns): an NIH-funded, multi-institutional and interdisciplinary project, which attempts to determine the etiology and pathogenesis of immediate and long-term complications in very preterm newborns. Principal Investigator: Dr. Alan Leviton, Boston Children’s Hospital, Harvard University.
Targeting Placental Pathophysiology in IUGR and Preeclampsia: Ob/Gyn ARRA Award 2R01HD033909-12A2. Principal Investigator: Dr. Seth Guller, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
sEGFR As a New Biomarker of Risk for Preterm Birth: submitted to Burroughs Wellcome Fund and to the Challenge Topic 04-HD-10: Identification of the Factors that Place Women at Risk for Preterm Birth. Principal Investigator: Dr. Nita Maihle, Departments of Obstetrics, Gynecology and Reproductive Sciences, Pathology and Pharmacology, Yale University.
Theranostics for preventing oxidative stress and poor outcome of preterm neonates. R01 NIH grant application submitted. Principal Investigator: Dr. Catalin S Buhimschi, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
Role of Toll-like Receptors and Glucocorticoids in Placental/Fetal Inflammation. R01 NIH grant application submitted. Principal Investigator: Dr. Seth Guller, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
Function of TLRs throughout gestation. R01 NIH program grant application submitted. Principal Investigator: Dr. Gil Mor, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
Ceruloplasmin as an early marker for pre-eclampsia. In collaboration with Dr. Seth Guller from the Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
PRESENTED LECTURES AND SEMINARS:
- "Introductory Course to Molecular Biology", at the Faculty of Medical Sciences, Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (September 20-24, 1993)
- "Oncogenes: Structure, Mechanisms of Activation, and the Role of Tumor Suppressor Genes as Carcinogenic Factors", at the National Institute of Oncology, Ecuadorian Society for the Fight Against Cancer (SOLCA), Guayaquil, Ecuador (April, 1995)
- Seminar "Introduction to Genetics in Medical Oncology", at the National Institute of Oncology, Ecuadorian Society for the Fight Against Cancer (SOLCA), Guayaquil, Ecuador (June 12 -23, 1995)
- "Molecular Biology of Cancer", at the VIII National Congress of Pathology; VI Ecuadorian Congress of Clinical Pathology; I Ecuadorian Congress of Laboratory Medicine, SOLCA Hospital, Cuenca, Ecuador (August 1-5, 1995)
- "Applications of Molecular Biology in Medicine", at the III Course "Selected Topics in Pediatrics", Faculty of Medicine and Post-Graduate School, Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (August 12, 1995)
- "Molecular Biology Workshop", "Applications of Molecular Biology in Tumors", and "Advances in the Diagnosis of Tropical Diseases by Molecular Biology", at the Seminar "Interpretation of Tumors and Tropical Diseases by Electron Microscope and Molecular Biology", National Institute of Hygiene and Tropical Medicine, Guayaquil, Ecuador (September 26-28, 1995)
- "Molecular Biology of Cancer", at the "Dr. Francisco Leone Divanna" II Biennial Medical Conference; II International Congress of Obstetrics and Gynecology, IESS Regional 2; I Congress of Post-Graduate Residents on Obstetrics and Gynecology. Dr. Teodororo Maldonado Carbo Regional Hospital of the Ecuadorian Institute of Social Security (IESS), Guayaquil, Ecuador (October 10- 13, 1995)
- "Applications of Molecular Biology in Medicine", and participated in the round table discussion at the symposium "Molecular Genetics and Psychiatry", Lorenzo Ponce Psychiatric Hospital, Guayaquil, Ecuador (October 16- 19, 1995)
- "Proto-oncogenes and Oncogenes", "Mechanisms of Activation of Proto-oncogenes", and "Anti-oncogenes", at the symposium "Current Topics in Molecular Biology of Cancer", Ecuadorian Oncology Research Group (GOIE), Dr. Teodoro Maldonado Carbo Regional Hospital of the Ecuadorian Institute of Social Security (IESS), Guayaquil, Ecuador (December 14, 1995)
- "Molecular Biology: Basic Concepts. Diagnostic and Therapeutic Applications", at the Academic Activity for Scholar Post-Graduate Clinical Oncology Residents, National Institute of Oncology, Ecuadorian Society for the Fight Against Cancer (SOLCA), Guayaquil, Ecuador (July 11, 1996)
- "Growth Factors", and "Oncogenes - Anti-oncogenes", at the III International Course of Oncology, Ecuadorian Oncology Research Group (GOIE), Dr. Teodoro Maldonado Carbo Regional Hospital of the Ecuadorian Institute of Social Security (IESS), Guayaquil, Ecuador (October 2, 1996)
- “Molecular Pathology of Cancer: from Morphology to Biology” and chaired the round table discussion, at the First International Course on Applications of Molecular Biology in Medicine, Institute of Tropical Molecular Biology, Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (August 31-September 4, 1998)
- “Molecular Pathology of Cancer: from Morphology to Biology”, at the National Institute of Oncology, Ecuadorian Society for the Fight Against Cancer (SOLCA), Guayaquil, Ecuador (September 4, 1998)
- “The Role of Molecular Pathology in the Delineation of New Entities: Clear Cell Papillary Renal Cell Carcinoma and Alveolar Soft Part Sarcoma”, at the Molecular Pathology Symposium of the XXIII Latin American Congress of Pathology, Latin American Society of Pathology (SLAP), Managua, Nicaragua (November 25-30, 2001)
- “Skeletal Dysplasias”, at the Pediatric Pathology Course, I National Congress of the Anatomic Pathology Federation of the Mexican Republic, and XLV National Congress of the Mexican Association of Pathologists, Ixtapa, México (May 1- 4, 2002)
- “Sclerosing Rhabdomyosarcoma”, at the Pediatric Surgical Pathology Seminar of the XXIV Latin American Congress of Pathology, Latin American Society of Pathology (SLAP), Quito, Ecuador (October 20-24, 2003)
- “Current Topics in Pediatric Surgical Pathology: Sclerosing Rhabdomyosarcoma”, at the XLVI National Meeting “Dr. Jose Angel Suarez”, Venezuelan Society of Anatomic Pathology, Caracas, Venezuela (November 13-15, 2003)
- “Sclerosing Rhabdomyosarcoma in Children”, “Abnormal Distribution and Hyperplasia of Thyroid C-cells in PTEN-associated Tumor Syndromes” and “Chromosomal Rearrangements in Subungual (Dupuytren’s) Exostosis and Bizarre Parosteal Osteochondromatous Proliferation”, at the II Atlantic Conference on Cancer, Santa Cruz de Tenerife, Canary Islands, Spain (February 12-14, 2004)
- “Cytogenetics and Molecular Biology in Childhood Neoplasias”, at the Pathology and Cytogenetics Workshop “ONCO ’04: Canarias Contra el Cáncer”, Puerto del Rosario, Fuerteventura, Canary Islands, Spain (February 15-18, 2004)
- Pediatric Pathology Seminar, IV National Congress of the Anatomic Pathology Federation of the Mexican Republic, and XLVII National Congress of the Mexican Association of Pathologists, Cancún, México (May 1- 4, 2004)
- “Applications of Molecular Biology and Cytogenetics Techniques in the Diagnosis of Pediatric Tumors”, at the I Iberoamerican Surgical Pathology and Molecular Oncopathology Meeting, and VII Venezuelan Pathology Congress “Dr. Alberto Angulo Ortega”, Venezuelan Society of Anatomic Pathology, Caracas, Venezuela (November 17-20, 2004)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors”, at the Fourth Asia Pacific Meeting of the International Academy of Pathology, Beijing, China (August 22-26, 2005)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors”, at the III Andean Pathology Meetings of the Medical College of Mérida “Dra. Ana Dávila de Arreaga”, Mérida, Venezuela (November 18-19, 2005)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors” and “Importance of Immunohistochemistry in the Diagnosis of Pediatric Tumors”, at the Hospital of Pediatric Specialties, Maracaibo, Venezuela (March 20-21, 2006)
- “Immunohistochemistry in the Diagnosis of Pediatric Tumors”, at the I Andean Pediatric Oncology Meeting of the Autonomous Institute of the University Hospital of Los Andes, Mérida, Venezuela (March 22-25, 2006)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors” and “Molecular Aspects of Non-Neoplastic Pediatric Pathology”, at the Second Atlantic Molecular Pathology Conference, Fuerteventura, Canary Islands, Spain (June 8-10, 2006)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors”, at the Instituto Oncológico Nacional- SOLCA and at the Hospital Luis Vernaza, Guayaquil, Ecuador (June 17 and 20, 2006)
- “Molecular Biology and Cytogenetics in Pediatric Solid Tumors”, at the Young Talents of Pathology seminar series, Children’s Hospital of Philadelphia, PA, USA (February 28, 2007)
- “Molecular and Surgical Pathology of Undifferentiated Small Cell Pediatric Tumors: An Update” and “Bone Tumors: Diagnostic Criteria and Update”, at the III Anatomic Pathology Update Meeting (organized by the Medical College of Wisconsin), Guayaquil, Ecuador (August 1-3, 2008)
- “Immunohistochemical Analysis of Small Round Blue Cell Tumors and Soft Tissue Neoplasms”, Histologic Prognostic Factors in Pediatric Solid Tumors” and Round Table, at the Integrated Oncology Meeting of the Venezuelan Society of Oncology, Caracas, Venezuela (October 10-12, 2008)
- “Soft Tissue Pathology I: Benign Myxoid Neoplasms”, “Soft Tissue Pathology II: Malignant Myxoid Neoplasms” and “Undifferentiated Soft Tissue Tumors Seminar”, at the XI Venezuelan Pathology Congress of the Venezuelan Society of Anatomic Pathology, Barquisimeto, Venezuela (October 23-25, 2008)
- Co-Chair at the Society for Pediatric Pathology Spring Meeting Platform Presentations, Boston, MA, USA (March 7, 2009)
- Bone and Soft Tissue Pathology, Unknown Slide Conference, Surgical Pathology Residents, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA (August 27, 2009)
List of publications:
Theses and Dissertation:
High School Baccalaureate Chemistry and Biology Specialty thesis: "Chromosomopathies", Colegio Salesiano Cristóbal Colón, Guayaquil, Ecuador (November, 1983)
Medical Doctorate dissertation: "Long term effects of cyclosporine on renal function in cadaveric kidney recipients on double vs. triple immunosuppressive therapy". Project performed at Jackson Memorial Medical Center, University of Miami, Florida, and presented at the Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (April, 1992)
Master of Science thesis: "Characterization of mutations on the adenylosuccinate lyase (ASL) gene in patients with ASL deficiency". Project performed at the Center for Human Genetics, Gasthuisberg University Hospital, Leuven, Belgium, and presented at the Inter-University Post-Graduate Programme of Tropical Molecular Biology, Faculty of Sciences, Free University of Brussels, Belgium (September, 1994)
Abstracts:
Roth D, Fernández J, Zambrano E, Burke G, Nery J, Esquenazi V, Miller J. (1992) Long term double vs. triple immunosuppressive therapy for cadaveric renal recipients. Journal of the American Society of Nephrology, 2, p 815.
Zambrano E, El-Hennawy M, Ehrenkranz R, Reyes-Múgica M. (2001) Total parenteral nutrition (TPN)-induced liver pathology. An autopsy series of 25 newborn cases. Laboratory Investigation, 81, No.1, and in Modern Pathology, 14, No. 1.
Zambrano E, Reyes-Múgica M. (2001) Hormonal activity may predict aggressive behavior in neuroblastoma. Laboratory Investigation, 81, No.1, and in Modern Pathology, 14, No. 1.
Zambrano E, Rosai J, Reyes-Múgica M. (2001) Sarcoma de células claras primario en intestino delgado: un simulador de tumor gastrointestinal estromal (GIST) [Primary small bowel stromal sarcoma: a gastrointestinal stromal tumor (GIST) simulator]. Patología (Mex) 39: S13.
El-Hennawy M, Zambrano E, Reyes-Múgica M, Ehrenkranz R. (2001) Relationship between clinical risk factors and pathological findings of liver injury in neonates receiving total parenteral nutrition (TPN). Pediatric Research, 49: 398A.
Zambrano E, Nose V, Richkind K, Gebhardt M, Hresko M, Kleinman P, Perez-Atayde A, Kozakewich H. (2003) Distinct chromosomal rearrangements in Dupuytren’s exostosis and Nora’s lesion. Laboratory Investigation, 83, No.1: 8P, and in Modern Pathology, 16, No. 1.
Zambrano E, Holm I, Pilarski RT, Perez-Atayde A, Kozakewich H, Shamberger RC, Nose V. (2003) Abnormal distribution and hyperplasia of thyroid C-cells in Cowden’s disease (CD)/ Bannayan-Ruvalcaba-Riley Syndrome (BRRS). Laboratory Investigation, 83, No.1: 8P, and in Modern Pathology, 16, No. 1.
Zambrano E, Perez-Atayde A, Ahrens W, Reyes-Múgica, M. (2004) Sclerosing rhabdomyosarcoma in children. Laboratory Investigation, 84, No.2: 277, and in Modern Pathology, 17, No.2: 275.
Zambrano E, Dotto J, Barrón LP, Reyes-Múgica M. (2005) The placenta as a fetal shield: lack of correlation between severe placental lesions and Apgar scores, or, behind every healthy baby there may or may not be a healthy placenta. Laboratory Investigation, 85, No.2 and Modern Pathology, 18, No. 2: 313.
Duo H, Zambrano E, Chi B, Gutiérrez MC, Yee H, Drut M, Drut R, Askin F, Reyes-Múgica M, Greco MA. (2005)Overexpression of epidermal growth factor receptor (EGFR) in congenital cystic airway malformation (CCAM) type I. Laboratory Investigation, 85, No.2 and Modern Pathology, 18, No. 2: 304.
Stock F, Cammarata Scalisi F, Zambrano E, Milano M. (2005) Tumor desmoplástico de células redondas pequeñas. Reporte de un caso en adolescente femenino [Desmoplastic small round blue cell tumor. Report of a case in an adolescent female patient]. Archivos Venezolanos de Puericultura y Pediatría, 68 (S1):5.
Stock F, Cammarata F, Castillo A, Gordon O, Zambrano E, Petrosino O, Arenas A, Milano M. (2005) Carcinoma epidermoide metastásico de origen incierto en un escolar masculino de 12 años [Metastatic squamous cell carcinoma of uncertain origin in a 12-year-old boy]. Dermatología Venezolana, 43(4):24.
Sarita-Reyes C, Reyes-Múgica M, Zambrano E (2006) Distinguishing amniotic bands from fetal skin by expression of cytokeratins in the diagnosis of amniotic band disruption sequence (ABS). Laboratory Investigation, 86, No. 2 and Modern Pathology, 19, No. 2: 332-333.
Sarita-Reyes C, Zambrano E, Dotto J, Reyes-Múgica M. Indoleamine 2,3-Dioxygenase Appears Normally Distributed in Placental Lesions Associated with Increased Risk of Loss of Pregnancy. A Preliminary Study. Presented as poster at the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
Zambrano E, Cajaiba M, Sarita-Reyes C, Reyes-Múgica M. Marked Elevation of Serum Alpha-Feto Protein in Patients with Beckwith-Wiedemann Syndrome (BWS) does not necessarily mean Hepatoblastoma. Presented as poster at the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
Sarita-Reyes C, Pashankar D, Reyes-Múgica M, Zambrano E. Microvillous Inclusion Disease (MID) in an Infant with Coarctation of the Aorta. Morphological, Histochemical, Immunohistochemical and Ultrastructural Features of a Rare Congenital Disorder in a Previously Unreported Association. Presented as poster the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
Borys D, CajaibaMM, Reyes-MúgicaM, ZambranoE, GuoH, YeeH, GutierrezMC, DrutR, Drut RM, Askin F, Greco MA.Screening for K-Ras Mutations in Congenital Cystic Airway Malformation (CCAM) of the Lung. Presented as poster at the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
De Stefano D, Zambrano E. Hypoplastic Right Heart Syndrome in Monozygotic Twins. Presented as poster at the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
Buhimschi C, Bhandari V, Zhao G, Rosenberg VA, Zambrano E, Cackovic M, Funai E, Buhimschi IA. (2007) Evidence for a role of inflammation in control of angiopoietin-1, angiopoietin-2 and of their novel antagonist soluble Yie-2 in pregnancies complicated by intra-amniotic inflammation. American Journal of Obstetrics and Gynecology, 197(6), Supplement 1: S67. Presented at the Society for Maternal-Fetal Medicine: 2008 28th Annual Meeting - The Pregnancy Meeting.
Ziai J, French CA, Zambrano E. NUT-Associated Carcinoma in the Salivary Gland of a Pediatric Patient. Presented as poster at the CAP Meeting, Washington DC, October 11-14, 2009. October issue of Archives of Pathology and Laboratory Medicine.
Van Patten K, Ornstein DL, Li P, McCabe M, Zambrano E. Fulminant gamma/delta T-cell lymphoma presenting as acute appendicitis: a post-mortem study. Presented as poster at the CAP meeting, Washington DC, October 11-14, 2009. October issue of Archives of Pathology and Laboratory Medicine.
Zambrano H, Areán-Cuns C, Vigliotti V, Lee SH, Zambrano E. Identification of Human Papillomavirus (HPV) Genotypes in Pediatric Laryngeal Papillomatosis (PLP), to be presented as Platform Presentation at the Society for Pediatric Pathology Meeting in March 20, 2010, Washington, D.C.
Case Reports:
Zambrano E, Marshalko S, Jaffe C, Hui P. (2002) Isolated non-ventricular myocardial compaction: clinical and molecular aspects of a rare cardiomyopathy. Laboratory Investigation, 82: 117-122.
Zambrano E, Reyes-Múgica M. (2003) Renal cell carcinoma with t(X;17): singular pediatric neoplasm with specific phenotype/ genotype features. Pediatric and Developmental Pathology, 6(1): 84-87.
Zambrano E, Esper F, Rosenberg R, Kim J, Reyes-Múgica M. (2003) Chronic granulomatous disease. Pediatric and Developmental Pathology, 6(6): 577-581.
Stock F, Zambrano E, Cammarata-Scalisi F, Gordon O, Castillo A, Gamboa J, Petrosino P, Arenas A, Milano M. (2005) Carcinoma epidermoide metastásico en escolar de sexo masculino [Metastatic squamous cell carcinoma in a 12 year-old boy]. Dermatología Peruana (ISSN 1028-7175), 15(3):249-253.
Zambrano E, Mejía-Mejía O, Bifulco C, Shin J, Reyes-Múgica M. (2006) Extranodal marginal zone B-cell lymphoma/ maltoma of the lip in a child. Case report and review of cutaneous lymphoid proliferations in childhood. International Journal of Surgical Pathology, 14(2):163-169.
Stock F, Zambrano E, Cammarata-Scalisi F, Milano M, Petrosino P, Arenas A, Valderrama-Landaeta JL. (2008) Tumor desmoplástico de células redondas pequeñas. Reporte de un caso y revisión de la literatura [Desmoplastic small round cell tumor. A case report in a 13-year-old girl]. Revista Médica de la Extensión Portuguesa - ULA. 2(1):11-16.
Theoharis CGA, Carling T, Buza N, Zambrano E, Sosa JA. (2008) Multinodular Goiter and Primary Hyperparathyroidism: A Circuitous Route to Diagnosing Metastatic Uveal Melanoma. Endocrine Pathology, 19(4):294-8.
Moliterno JA, Sood S, Zambrano E, Kim JH, Piepmeier JM, Baehring JM. (2009) Intracranial Benign Fibrous Histiocytomas: A Case Report and Review. Journal of Neuro-Oncology J Neurooncol, 92(2):203-209.
Esquibies AE, Zambrano E, Ziai J, Kesebir D, Touloukian RJ, Egan ME , Reyes-Múgica M, Bazzy-Asaad A.(2010) Pulmonary Squamous Cell Carcinoma Associated with Repaired Congenital Tracheoesophageal Fistula and Esophageal Atresia. Pediatric Pulmonology, 45(2):202-4.
Ziai J, French CA, Zambrano E. NUT gene rearrangement in a poorly-differentiated carcinoma of the submandibular gland. Head and Neck Pathology. In press.
León-Ferré R, Friedlaender G, Vanegas T, Zambrano E. Post-radiation osteosarcoma in two young patients: Case reports and review of literature. In preparation.
Malhotra Y and Fitzgerald TN, Diefenbach KA, Harper H, Zambrano E, Cicero S, Moss RL, Bhandari V. A curious case of hemoperitoneum in a neonate: Case report and a review of rhabdoid tumors. In preparation.
Review Articles:
Ruiz JC, Zambrano EV, Ruiz EA. (1995) Análisis de asociación genética [Linkage analysis]. Revista Científica Medicina (ISSN 1390-0218), 1, No.3, 104- 109.
Zambrano EV. (1996) Biología molecular del cáncer [Molecular biology of cancer]. Oncología (ISSN 1390-0110), 6, No. 2, 181-188.
Zambrano-Tola E. (1996) Mecanismos moleculares de activación oncogénica [Molecular mechanisms of oncogenic activation]. Oncología (ISSN 1390-0110), 6(4):390-6.
Zambrano-Tola E, Merino-Espinoza M. (1997) Técnicas de diagnóstico molecular [Molecular diagnostic techniques]. Oncología (ISSN 1390-0110), 7(2):137-42.
Camelo-Piragua SI, Zambrano E, Pantanowitz L. Langerhans cell histiocytosis. Ear, Nose and Throat Journal (in press).
Original Papers:
Zambrano EV, Cuppens H, Legius E, Ruiz JC, Cassiman JJ. (1996) Caracterización de mutaciones en el gen de la adenilosuccinato liasa (ASL) en un paciente con epilepsia, retardo psicomotor y autismo [Characterization of mutations in the adenylosuccinate lyase gene (ASL) in a patient with epilepsy, psychomotor retardation and autism]. Revista Científica Medicina (ISSN 1390-0218), 2, No. 2, 99-104.
Zambrano-Tola E, Merino-Espinoza M. (1996) Estudio defamilias (pedigree) de pacientes con hemofilia A, fibrosis quística y síndrome del cromosoma X frágil, identificados en hospitales de la ciudad de Guayaquil [Family studies (pedigree) of patients with hemophilia A, cystic fibrosis and fragile X syndrome, identified from hospitals in the city of Guayaquil]. Revista de Investigación de laUniversidad Católica de Santiago de Guayaquil, 9, 7-30.
Marie E, Cuppens H, Heuterspreute M, Jaspers M, Zambrano-Tola E, Gu XX, Legius E, Vincent MF, Jaeken J, Cassiman JJ, Van den Berghe G. (1999) Mutation analysis in adenylosuccinate lyase deficiency: eight novel mutations in the re-evaluated full ADSL coding sequence. Human Mutation. 13: 197-202.
Zambrano E, Reyes-Múgica M. (2002) Hormonal activity may predict aggressive behavior in neuroblastoma. Pediatric and Developmental Pathology. 5 (2): 190-199.
Zambrano E, Reyes-Múgica M, Franchi A, Rosai J. (2003) An osteoclast-rich tumor of the gastrointesinal tract with features resembling clear cell sarcoma of soft parts: reports of six cases of a GIST simulator. International Journal of Surgical Pathology. 11(2):75-81.
Zambrano E, Holm I, Glickman J, Huang S, Perez-Atayde A, Kozakewich HPW, Shamberger RC, Nosé V. (2004) Abnormal distribution and hyperplasia of thyroid C-cells in PTEN-associated tumor syndromes. Endocrine Pathology. 15(1):55-64.
Zambrano E, Nose V, Richkind K, Gebhardt M, Hresko M, Kleinman P, Perez-Atayde A, Kozakewich H. (2004) Distinct chromosomal rearrangements in Dupuytren’s exostosis and Nora’s lesion. American Journal of Surgical Pathology. 28(8): 1033-1039.
Zambrano E, El-Hennawy M, Ehrenkranz R, Reyes-Múgica M. (2004) Total parenteral nutrition (TPN)-induced liver pathology. An autopsy series of 24 newborn cases. Pediatric and Developmental Pathology. 7(5): 425-432.
Zambrano E, Pérez-Atayde A, Ahrens W, Reyes-Múgica M. (2006) Pediatric Sclerosing Rhabdomyosarcoma. International Journal of Surgical Pathology. 14(3): 193-197.
Cajaiba MM, Sarita-Reyes C, Zambrano E, Miguel Reyes-Múgica. (2007) Mesenchymal Hamartoma of the Liver Associated with Beckwith-Wiedemann Syndrome Features and High Serum Alphafetoprotein Levels. Pediatric and Developmental Pathology. 10(3): 233-238.
Kenney B, Richkind KE, Zambrano E. (2007) Solid Variant of Aneurysmal Bone Cyst with a Novel (X;9) Translocation. Cancer Genetics and Cytogenetics. 178(2):155-159.
Hecht JL, Kliman HJ, Allred EN, Pflueger SMV, Chang CH, Doss B, Roberts D, Livasy C, Bhan I, Zambrano E, Ross DW, Senagore P, Husain A, Leviton A. (2007) Reference weights for placentas delivered before the 28th week of gestation. Placenta. 28(10):987-990.
Kenney B, Richkind KE, Friedlaender G, Zambrano E. (2007)Chromosomal Rearrangements In Lipofibromatosis. Cancer Genetics and Cytogenetics. 179:136-139.
Kim J, Zambrano E, McNiff JM. (2007) Congenital Panfollicular Nevus Associated with Polydactyly. Journal of Cutaneous Pathology. 34 (Suppl. 1):14-17.
De Stefano D, Peining L, Xiang B, Hui P, Zambrano E. (2008) Pulmonary atresia with intact ventricular septum (PA-IVS) in monozygotic twins. Am J Med Genet A.146A(4):525-528.
Buhimschi IA, Zambrano E, Pettker CM, Bahtiyar MO, Paidas M, Rosenberg VA, Thung S, Salafia CM, Buhimschi CS. (2008) Using proteomic analysis of the human amniotic fluid to identify histological chorioamnionitis. Obstet Gynecol. 111(2):403-412.
Hecht JL, Onderdonk A, Delaney M, Allred EN, Kliman HJ, Zambrano E, Solveig P, Livasy C, Bhan I, Leviton A. (2008) Characterization of chorioamnionitis in second trimester c-section placentas and correlation with microorganism recovery from sub-amniotic tissues. Pediatr Dev Pathol. 11(1):15-22.
Gathungu GN, Pashankar DS, Sarita-Reyes CD, Zambrano E, Reyes-Mugica M, Brueckner M, Mistry PK, Husain SZ. (2008) Microvillus Inclusion Disease Associated With Coarctation of the Aorta and Bicuspid Aortic Valve. J Clin Gastroenterol. 42(4):400-403.
Hecht JL, Allred EN, Kliman HJ, Zambrano E, Doss B, Husain A, Pflueger SMV, Chang C, Livasy C, Roberts D, Bhan I, Ross DW, Senagore PK, Leviton A. (2008) Histologic characteristics of placentas delivered before the 28th week of gestation. Pathology, 40(4):372-376.
Buhimschi CS, Abdel-Razeq S,Cackovik M, Pettker CM, Dulay AT, Mert-Ozan B, Zambrano E, Martin R, Norwitz ER,Bhandari V, Buhimschi IA. (2008) FHR monitoring patterns in women with amniotic fluid proteomic profiles indicative of inflammation. American Journal of Perinatology, 25(6):359-372.
Guller S, Buhimschi CS, Ma YY, Huang STJ, Yang L, Kuczynski E, ZambranoE, LockwoodCJ, Buhimschi IA. (2008) Placental Expression of Ceruloplasmin in Pregnancies with Severe Preeclampsia. Laboratory Investigation, 88:1057–1067.
McElrath TF, Hecht JL, Dammann O, Boggess K, Onderdonk A, Markenson G, Harper M, Delpapa E, Allred EN, Leviton A; ELGAN Study Investigators. (2008) Pregnancy disorders that lead to delivery before the 28th week of gestation: an epidemiologic approach to classification. Am J Epidemiol, 168(9):980-989.
Onderdonk AB, Hecht JL, McElrath TF, Delaney ML, Allred EN, Leviton A; ELGAN Study Investigators. (2008) Colonization of second-trimester placenta parenchyma. Am J Obstet Gynecol, 199(1):52.e1-52.e10.
McElrath TF, Allred EN, Boggess KA, Kuban K, O'Shea TM, Paneth N, Leviton A; ELGAN Study Investigators. (2009) Maternal antenatal complications and the risk of neonatal cerebral white matter damage and later cerebral palsy in children born at an extremely low gestational age. Am J Epidemiol, 170(7):819-828.
Book Chapters:
Astudillo-De la Vega H, Zambrano E. (2008) “New Strategies in the Diagnosis and Treatment of Cancer”, In: Molecular Biology of Cancer, Clínicas Oncológicas de Iberoamérica Series, México DF, México, 264 pp.
León-Ferré R, Areán-Cuns C, Zambrano E. (2009) “Cytogenetic and Molecular Aspects of Bone and Soft Tissue Neoplasms”, In: Avances en Patología, 5th ed, Ed. Cabildo de Fuerteventura, Spain.
León-Ferré R, Areán-Cuns C, Zambrano E. (2009) “Genetic Syndromes Associated with Sarcomas”, In: Avances en Patología, 5th ed, Ed. Cabildo de Fuerteventura, Spain.
Textbooks:
Zambrano-Tola, Eduardo (1996) Introducción a la Biología Molecular [Introduction to Molecular Biology], 1st ed., Editorial Universitaria - Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador.
(IPMB 1994)
Positions held since graduation:
CERTIFICATIONS
Educational Commission for Foreign Medical Graduates (ECFMG), 1997
Anatomic and Clinical Pathology, American Board of Pathology, 2003
Pediatric Pathology, American Board of Pathology, 2003
RESIDENCY AND FELLOWSHIP TRAINING:
Clinical Fellow in Pediatric Pathology, Boston Children’s Hospital, Harvard Medical School. Boston, MA (July 2002 – June 2003)
Comined Anatomic and Clinical Pathology Residency Programs (AP/CP), Departments of Pathology and Laboratory Medicine, Yale-New Haven Hospital, Yale University School of Medicine. New Haven, CT (July 1997 - June 2002)
PROFESSIONAL EXPERIENCE:
Academic Appointments:
Associate Professor, Department of Pathology, Medical College of Wisconsin. Milwaukee, WI (since January 1, 2010)
Associate Professor, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2009 – December 31, 2009)
Assistant Professor, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2004 - June 30, 2009)
Instructor, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2003 - June 30, 2004)
Professor, School of Medicine, Universidad Católica de Santiago de Guayaquil. Guayaquil, Ecuador (since 1996)
Clinical Experience:
Consultant, Musculoskeletal Pathology, Department of Pathology, Yale University School of Medicine. New Haven, CT (January 2007 – December 2009)
Attending Pathologist, Department of Pathology, Milford Hospital. Milford, CT (May 1, 2008 – December 31, 2009)
Attending Pathologist, Department of Pathology, Yale-New Haven Hospital. New Haven, CT (July 1, 2003 – December 31, 2009)
Attending Pathologist, Department of Pathology, Bridgeport Hospital. Bridgeport, CT (July 1, 2003 – December 31, 2009)
Teaching Experience:
Lecturer, Bone and Soft Tissue Pathology, second-year medical students, Medical College of Wisconsin. Milwaukee, WI (since January 2010)
Lecturer, Pediatric Pathology Overview and Developmental Disorders of the Musculoskeletal System.General Principles of Pathology Course for first-year medical students, Yale University School of Medicine (2008-2009)
Director, Pathology labs and lectures. Cardiovascular Module, Mechanism of Disease Course, Yale University School of Medicine. New Haven, CT (2006-2009)
Lecturer, Pathology of Pediatric Solid Tumors. Seminar series for Pediatric Oncology Attendings, Fellows and Advanced Practitioners, Department of Pediatrics, Yale University School of Medicine (2008-2009)
Co-leader, Pathology Course Tutorials for second-year medical students, Yale University School of Medicine (2003-2007)
Lecturer, Cardiovascular Pathology. Pathology Lecture series for first-year students, Physician Associate Program, Yale University School of Medicine (2003-2009)
Head Professor of Biology, Faculty of Medical Sciences, Universidad Católica de Santiago de Guayaquil (UCSG) (March 1996 – June 1997)
Visiting Professor of Biology, Faculty of Medical Sciences, Universidad Católica de Santiago de Guayaquil (UCSG) (March 1995 - March 1996)
Invited Professor of Biology. Undergraduate Faculty of Medical Sciences. Universidad Católica de Santiago de Guayaquil (UCSG) (July - September 1993)
Administrative Experience:
Director, Surgical Pathology, Department of Pathology, Medical College of Wisconsin. Milwaukee, WI (since January 1, 2010)
Director, Musculoskeletal Pathology Service, Department of Pathology, Medical College of Wisconsin. Milwaukee, WI (since January 1, 2010)
Director, Orthopaedic Pathology, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2009 – December 31, 2009)
Director, Pediatric and Developmental Pathology, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2008 – December 31, 2009)
Associate Director, Anatomic Pathology Residency Program, Department of Pathology, Yale University School of Medicine. New Haven, CT (November 2008 – November 2009)
Assistant Director, Autopsy Service, Department of Pathology, Yale University School of Medicine. New Haven, CT (July 1, 2007 – December 31, 2009)
Secretary/ Treasurer, Latin American Pathology Foundation (LAPF) (March 2006 – March 2009) and Manager of the LAPF website (since February 2008)
Member,Residency Selection Committee, Department of Pathology, Yale-New Haven Hospital, Yale University School of Medicine. New Haven, CT (2004-2005, 2006-2007 and 2008-2009)
Administrative Chief Resident, Department of Pathology, Yale-New Haven Hospital, Yale University School of Medicine. New Haven, CT (July 2001 - June 2002)
Inspector (# 705549), for the College of American Pathologists (May 2001 and September 2004)
Acting Director, Instituto de Biología Molecular Tropical [Institute of Tropical Molecular Biology] (IBMT), Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (August 1995 - May 1997)
Editorial Experience:
Member, Editorial Board, Annals of Diagnostic Pathology (since January 2010)
Member, Scientific Committee, X Virtual Hispanic-American Anatomical Pathology Meeting (2009)
Member, Editorial Board, Pediatric and Developmental Pathology [official Journal of the Society for Pediatric Pathology, ISSN 1093-5266 (printed version), ISSN 1615-5742 (electronic version)] (March, 2004-June, 2007)
Reviewer, Pediatric and Developmental Pathology (2000-2004)
Reviewer, Journal of Medical Case Reports (2008)
Reviewer, Histology and Histopathology (2009)
SOCIETY MEMBERSHIPS:
Fellow, College of American Pathologists (CAP)
Member, American Medical Association (AMA)
Member, United States and Canadian Academy of Pathology (USCAP)
Member, Society for Pediatric Pathology (SPP)
Member, Nominating Committee, Society for Pediatric Pathology (2005-2008)
Member, International Society of Bone and Soft Tissue Pathology (ISBSTP)
Member, Arkadi M. Rywlin International Pathology Club
Member, American Diabetes Association
Associate Member, Endocrine Pathology Society (EPS)
Member, Children’s Hospital Boston Alumni Association
Active Member and former Chair of Members Committee, Latin American Pathology Foundation (LAPF)
Founding Member, Dr. Roberto Gilbert Elizalde Foundation, a foundation for the advancement and development of molecular biology in Guayaquil, Ecuador
Associate Member, Colegio Ecuatoriano de Cirujanos [Ecuadorian College of Surgeons]
Active Member, Sociedad Ecuatoriana de Colo-Proctología [Ecuadorian Society of Colo-Proctology]
Former member, Board of Directors, Hispanos Unidos, a foundation for support and community programs for the Hispanic population with AIDS and other diseases, based in New Haven, CT (October 2000 - October 2001)
Projects involved in:
ELGAN (Extremely Low Gestational Age Newborns): an NIH-funded, multi-institutional and interdisciplinary project, which attempts to determine the etiology and pathogenesis of immediate and long-term complications in very preterm newborns. Principal Investigator: Dr. Alan Leviton, Boston Children’s Hospital, Harvard University.
Targeting Placental Pathophysiology in IUGR and Preeclampsia: Ob/Gyn ARRA Award 2R01HD033909-12A2. Principal Investigator: Dr. Seth Guller, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
sEGFR As a New Biomarker of Risk for Preterm Birth: submitted to Burroughs Wellcome Fund and to the Challenge Topic 04-HD-10: Identification of the Factors that Place Women at Risk for Preterm Birth. Principal Investigator: Dr. Nita Maihle, Departments of Obstetrics, Gynecology and Reproductive Sciences, Pathology and Pharmacology, Yale University.
Theranostics for preventing oxidative stress and poor outcome of preterm neonates. R01 NIH grant application submitted. Principal Investigator: Dr. Catalin S Buhimschi, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
Role of Toll-like Receptors and Glucocorticoids in Placental/Fetal Inflammation. R01 NIH grant application submitted. Principal Investigator: Dr. Seth Guller, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
Function of TLRs throughout gestation. R01 NIH program grant application submitted. Principal Investigator: Dr. Gil Mor, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
Ceruloplasmin as an early marker for pre-eclampsia. In collaboration with Dr. Seth Guller from the Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University.
PRESENTED LECTURES AND SEMINARS:
- "Introductory Course to Molecular Biology", at the Faculty of Medical Sciences, Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (September 20-24, 1993)
- "Oncogenes: Structure, Mechanisms of Activation, and the Role of Tumor Suppressor Genes as Carcinogenic Factors", at the National Institute of Oncology, Ecuadorian Society for the Fight Against Cancer (SOLCA), Guayaquil, Ecuador (April, 1995)
- Seminar "Introduction to Genetics in Medical Oncology", at the National Institute of Oncology, Ecuadorian Society for the Fight Against Cancer (SOLCA), Guayaquil, Ecuador (June 12 -23, 1995)
- "Molecular Biology of Cancer", at the VIII National Congress of Pathology; VI Ecuadorian Congress of Clinical Pathology; I Ecuadorian Congress of Laboratory Medicine, SOLCA Hospital, Cuenca, Ecuador (August 1-5, 1995)
- "Applications of Molecular Biology in Medicine", at the III Course "Selected Topics in Pediatrics", Faculty of Medicine and Post-Graduate School, Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (August 12, 1995)
- "Molecular Biology Workshop", "Applications of Molecular Biology in Tumors", and "Advances in the Diagnosis of Tropical Diseases by Molecular Biology", at the Seminar "Interpretation of Tumors and Tropical Diseases by Electron Microscope and Molecular Biology", National Institute of Hygiene and Tropical Medicine, Guayaquil, Ecuador (September 26-28, 1995)
- "Molecular Biology of Cancer", at the "Dr. Francisco Leone Divanna" II Biennial Medical Conference; II International Congress of Obstetrics and Gynecology, IESS Regional 2; I Congress of Post-Graduate Residents on Obstetrics and Gynecology. Dr. Teodororo Maldonado Carbo Regional Hospital of the Ecuadorian Institute of Social Security (IESS), Guayaquil, Ecuador (October 10- 13, 1995)
- "Applications of Molecular Biology in Medicine", and participated in the round table discussion at the symposium "Molecular Genetics and Psychiatry", Lorenzo Ponce Psychiatric Hospital, Guayaquil, Ecuador (October 16- 19, 1995)
- "Proto-oncogenes and Oncogenes", "Mechanisms of Activation of Proto-oncogenes", and "Anti-oncogenes", at the symposium "Current Topics in Molecular Biology of Cancer", Ecuadorian Oncology Research Group (GOIE), Dr. Teodoro Maldonado Carbo Regional Hospital of the Ecuadorian Institute of Social Security (IESS), Guayaquil, Ecuador (December 14, 1995)
- "Molecular Biology: Basic Concepts. Diagnostic and Therapeutic Applications", at the Academic Activity for Scholar Post-Graduate Clinical Oncology Residents, National Institute of Oncology, Ecuadorian Society for the Fight Against Cancer (SOLCA), Guayaquil, Ecuador (July 11, 1996)
- "Growth Factors", and "Oncogenes - Anti-oncogenes", at the III International Course of Oncology, Ecuadorian Oncology Research Group (GOIE), Dr. Teodoro Maldonado Carbo Regional Hospital of the Ecuadorian Institute of Social Security (IESS), Guayaquil, Ecuador (October 2, 1996)
- “Molecular Pathology of Cancer: from Morphology to Biology” and chaired the round table discussion, at the First International Course on Applications of Molecular Biology in Medicine, Institute of Tropical Molecular Biology, Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (August 31-September 4, 1998)
- “Molecular Pathology of Cancer: from Morphology to Biology”, at the National Institute of Oncology, Ecuadorian Society for the Fight Against Cancer (SOLCA), Guayaquil, Ecuador (September 4, 1998)
- “The Role of Molecular Pathology in the Delineation of New Entities: Clear Cell Papillary Renal Cell Carcinoma and Alveolar Soft Part Sarcoma”, at the Molecular Pathology Symposium of the XXIII Latin American Congress of Pathology, Latin American Society of Pathology (SLAP), Managua, Nicaragua (November 25-30, 2001)
- “Skeletal Dysplasias”, at the Pediatric Pathology Course, I National Congress of the Anatomic Pathology Federation of the Mexican Republic, and XLV National Congress of the Mexican Association of Pathologists, Ixtapa, México (May 1- 4, 2002)
- “Sclerosing Rhabdomyosarcoma”, at the Pediatric Surgical Pathology Seminar of the XXIV Latin American Congress of Pathology, Latin American Society of Pathology (SLAP), Quito, Ecuador (October 20-24, 2003)
- “Current Topics in Pediatric Surgical Pathology: Sclerosing Rhabdomyosarcoma”, at the XLVI National Meeting “Dr. Jose Angel Suarez”, Venezuelan Society of Anatomic Pathology, Caracas, Venezuela (November 13-15, 2003)
- “Sclerosing Rhabdomyosarcoma in Children”, “Abnormal Distribution and Hyperplasia of Thyroid C-cells in PTEN-associated Tumor Syndromes” and “Chromosomal Rearrangements in Subungual (Dupuytren’s) Exostosis and Bizarre Parosteal Osteochondromatous Proliferation”, at the II Atlantic Conference on Cancer, Santa Cruz de Tenerife, Canary Islands, Spain (February 12-14, 2004)
- “Cytogenetics and Molecular Biology in Childhood Neoplasias”, at the Pathology and Cytogenetics Workshop “ONCO ’04: Canarias Contra el Cáncer”, Puerto del Rosario, Fuerteventura, Canary Islands, Spain (February 15-18, 2004)
- Pediatric Pathology Seminar, IV National Congress of the Anatomic Pathology Federation of the Mexican Republic, and XLVII National Congress of the Mexican Association of Pathologists, Cancún, México (May 1- 4, 2004)
- “Applications of Molecular Biology and Cytogenetics Techniques in the Diagnosis of Pediatric Tumors”, at the I Iberoamerican Surgical Pathology and Molecular Oncopathology Meeting, and VII Venezuelan Pathology Congress “Dr. Alberto Angulo Ortega”, Venezuelan Society of Anatomic Pathology, Caracas, Venezuela (November 17-20, 2004)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors”, at the Fourth Asia Pacific Meeting of the International Academy of Pathology, Beijing, China (August 22-26, 2005)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors”, at the III Andean Pathology Meetings of the Medical College of Mérida “Dra. Ana Dávila de Arreaga”, Mérida, Venezuela (November 18-19, 2005)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors” and “Importance of Immunohistochemistry in the Diagnosis of Pediatric Tumors”, at the Hospital of Pediatric Specialties, Maracaibo, Venezuela (March 20-21, 2006)
- “Immunohistochemistry in the Diagnosis of Pediatric Tumors”, at the I Andean Pediatric Oncology Meeting of the Autonomous Institute of the University Hospital of Los Andes, Mérida, Venezuela (March 22-25, 2006)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors” and “Molecular Aspects of Non-Neoplastic Pediatric Pathology”, at the Second Atlantic Molecular Pathology Conference, Fuerteventura, Canary Islands, Spain (June 8-10, 2006)
- “Applications of Molecular Biology and Cytogenetics in Pediatric Tumors”, at the Instituto Oncológico Nacional- SOLCA and at the Hospital Luis Vernaza, Guayaquil, Ecuador (June 17 and 20, 2006)
- “Molecular Biology and Cytogenetics in Pediatric Solid Tumors”, at the Young Talents of Pathology seminar series, Children’s Hospital of Philadelphia, PA, USA (February 28, 2007)
- “Molecular and Surgical Pathology of Undifferentiated Small Cell Pediatric Tumors: An Update” and “Bone Tumors: Diagnostic Criteria and Update”, at the III Anatomic Pathology Update Meeting (organized by the Medical College of Wisconsin), Guayaquil, Ecuador (August 1-3, 2008)
- “Immunohistochemical Analysis of Small Round Blue Cell Tumors and Soft Tissue Neoplasms”, Histologic Prognostic Factors in Pediatric Solid Tumors” and Round Table, at the Integrated Oncology Meeting of the Venezuelan Society of Oncology, Caracas, Venezuela (October 10-12, 2008)
- “Soft Tissue Pathology I: Benign Myxoid Neoplasms”, “Soft Tissue Pathology II: Malignant Myxoid Neoplasms” and “Undifferentiated Soft Tissue Tumors Seminar”, at the XI Venezuelan Pathology Congress of the Venezuelan Society of Anatomic Pathology, Barquisimeto, Venezuela (October 23-25, 2008)
- Co-Chair at the Society for Pediatric Pathology Spring Meeting Platform Presentations, Boston, MA, USA (March 7, 2009)
- Bone and Soft Tissue Pathology, Unknown Slide Conference, Surgical Pathology Residents, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA (August 27, 2009)
List of publications:
Theses and Dissertation:
High School Baccalaureate Chemistry and Biology Specialty thesis: "Chromosomopathies", Colegio Salesiano Cristóbal Colón, Guayaquil, Ecuador (November, 1983)
Medical Doctorate dissertation: "Long term effects of cyclosporine on renal function in cadaveric kidney recipients on double vs. triple immunosuppressive therapy". Project performed at Jackson Memorial Medical Center, University of Miami, Florida, and presented at the Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador (April, 1992)
Master of Science thesis: "Characterization of mutations on the adenylosuccinate lyase (ASL) gene in patients with ASL deficiency". Project performed at the Center for Human Genetics, Gasthuisberg University Hospital, Leuven, Belgium, and presented at the Inter-University Post-Graduate Programme of Tropical Molecular Biology, Faculty of Sciences, Free University of Brussels, Belgium (September, 1994)
Abstracts:
Roth D, Fernández J, Zambrano E, Burke G, Nery J, Esquenazi V, Miller J. (1992) Long term double vs. triple immunosuppressive therapy for cadaveric renal recipients. Journal of the American Society of Nephrology, 2, p 815.
Zambrano E, El-Hennawy M, Ehrenkranz R, Reyes-Múgica M. (2001) Total parenteral nutrition (TPN)-induced liver pathology. An autopsy series of 25 newborn cases. Laboratory Investigation, 81, No.1, and in Modern Pathology, 14, No. 1.
Zambrano E, Reyes-Múgica M. (2001) Hormonal activity may predict aggressive behavior in neuroblastoma. Laboratory Investigation, 81, No.1, and in Modern Pathology, 14, No. 1.
Zambrano E, Rosai J, Reyes-Múgica M. (2001) Sarcoma de células claras primario en intestino delgado: un simulador de tumor gastrointestinal estromal (GIST) [Primary small bowel stromal sarcoma: a gastrointestinal stromal tumor (GIST) simulator]. Patología (Mex) 39: S13.
El-Hennawy M, Zambrano E, Reyes-Múgica M, Ehrenkranz R. (2001) Relationship between clinical risk factors and pathological findings of liver injury in neonates receiving total parenteral nutrition (TPN). Pediatric Research, 49: 398A.
Zambrano E, Nose V, Richkind K, Gebhardt M, Hresko M, Kleinman P, Perez-Atayde A, Kozakewich H. (2003) Distinct chromosomal rearrangements in Dupuytren’s exostosis and Nora’s lesion. Laboratory Investigation, 83, No.1: 8P, and in Modern Pathology, 16, No. 1.
Zambrano E, Holm I, Pilarski RT, Perez-Atayde A, Kozakewich H, Shamberger RC, Nose V. (2003) Abnormal distribution and hyperplasia of thyroid C-cells in Cowden’s disease (CD)/ Bannayan-Ruvalcaba-Riley Syndrome (BRRS). Laboratory Investigation, 83, No.1: 8P, and in Modern Pathology, 16, No. 1.
Zambrano E, Perez-Atayde A, Ahrens W, Reyes-Múgica, M. (2004) Sclerosing rhabdomyosarcoma in children. Laboratory Investigation, 84, No.2: 277, and in Modern Pathology, 17, No.2: 275.
Zambrano E, Dotto J, Barrón LP, Reyes-Múgica M. (2005) The placenta as a fetal shield: lack of correlation between severe placental lesions and Apgar scores, or, behind every healthy baby there may or may not be a healthy placenta. Laboratory Investigation, 85, No.2 and Modern Pathology, 18, No. 2: 313.
Duo H, Zambrano E, Chi B, Gutiérrez MC, Yee H, Drut M, Drut R, Askin F, Reyes-Múgica M, Greco MA. (2005)Overexpression of epidermal growth factor receptor (EGFR) in congenital cystic airway malformation (CCAM) type I. Laboratory Investigation, 85, No.2 and Modern Pathology, 18, No. 2: 304.
Stock F, Cammarata Scalisi F, Zambrano E, Milano M. (2005) Tumor desmoplástico de células redondas pequeñas. Reporte de un caso en adolescente femenino [Desmoplastic small round blue cell tumor. Report of a case in an adolescent female patient]. Archivos Venezolanos de Puericultura y Pediatría, 68 (S1):5.
Stock F, Cammarata F, Castillo A, Gordon O, Zambrano E, Petrosino O, Arenas A, Milano M. (2005) Carcinoma epidermoide metastásico de origen incierto en un escolar masculino de 12 años [Metastatic squamous cell carcinoma of uncertain origin in a 12-year-old boy]. Dermatología Venezolana, 43(4):24.
Sarita-Reyes C, Reyes-Múgica M, Zambrano E (2006) Distinguishing amniotic bands from fetal skin by expression of cytokeratins in the diagnosis of amniotic band disruption sequence (ABS). Laboratory Investigation, 86, No. 2 and Modern Pathology, 19, No. 2: 332-333.
Sarita-Reyes C, Zambrano E, Dotto J, Reyes-Múgica M. Indoleamine 2,3-Dioxygenase Appears Normally Distributed in Placental Lesions Associated with Increased Risk of Loss of Pregnancy. A Preliminary Study. Presented as poster at the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
Zambrano E, Cajaiba M, Sarita-Reyes C, Reyes-Múgica M. Marked Elevation of Serum Alpha-Feto Protein in Patients with Beckwith-Wiedemann Syndrome (BWS) does not necessarily mean Hepatoblastoma. Presented as poster at the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
Sarita-Reyes C, Pashankar D, Reyes-Múgica M, Zambrano E. Microvillous Inclusion Disease (MID) in an Infant with Coarctation of the Aorta. Morphological, Histochemical, Immunohistochemical and Ultrastructural Features of a Rare Congenital Disorder in a Previously Unreported Association. Presented as poster the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
Borys D, CajaibaMM, Reyes-MúgicaM, ZambranoE, GuoH, YeeH, GutierrezMC, DrutR, Drut RM, Askin F, Greco MA.Screening for K-Ras Mutations in Congenital Cystic Airway Malformation (CCAM) of the Lung. Presented as poster at the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
De Stefano D, Zambrano E. Hypoplastic Right Heart Syndrome in Monozygotic Twins. Presented as poster at the International Academy of Pathology in Montreal, Canada, September 16-21, 2006.
Buhimschi C, Bhandari V, Zhao G, Rosenberg VA, Zambrano E, Cackovic M, Funai E, Buhimschi IA. (2007) Evidence for a role of inflammation in control of angiopoietin-1, angiopoietin-2 and of their novel antagonist soluble Yie-2 in pregnancies complicated by intra-amniotic inflammation. American Journal of Obstetrics and Gynecology, 197(6), Supplement 1: S67. Presented at the Society for Maternal-Fetal Medicine: 2008 28th Annual Meeting - The Pregnancy Meeting.
Ziai J, French CA, Zambrano E. NUT-Associated Carcinoma in the Salivary Gland of a Pediatric Patient. Presented as poster at the CAP Meeting, Washington DC, October 11-14, 2009. October issue of Archives of Pathology and Laboratory Medicine.
Van Patten K, Ornstein DL, Li P, McCabe M, Zambrano E. Fulminant gamma/delta T-cell lymphoma presenting as acute appendicitis: a post-mortem study. Presented as poster at the CAP meeting, Washington DC, October 11-14, 2009. October issue of Archives of Pathology and Laboratory Medicine.
Zambrano H, Areán-Cuns C, Vigliotti V, Lee SH, Zambrano E. Identification of Human Papillomavirus (HPV) Genotypes in Pediatric Laryngeal Papillomatosis (PLP), to be presented as Platform Presentation at the Society for Pediatric Pathology Meeting in March 20, 2010, Washington, D.C.
Case Reports:
Zambrano E, Marshalko S, Jaffe C, Hui P. (2002) Isolated non-ventricular myocardial compaction: clinical and molecular aspects of a rare cardiomyopathy. Laboratory Investigation, 82: 117-122.
Zambrano E, Reyes-Múgica M. (2003) Renal cell carcinoma with t(X;17): singular pediatric neoplasm with specific phenotype/ genotype features. Pediatric and Developmental Pathology, 6(1): 84-87.
Zambrano E, Esper F, Rosenberg R, Kim J, Reyes-Múgica M. (2003) Chronic granulomatous disease. Pediatric and Developmental Pathology, 6(6): 577-581.
Stock F, Zambrano E, Cammarata-Scalisi F, Gordon O, Castillo A, Gamboa J, Petrosino P, Arenas A, Milano M. (2005) Carcinoma epidermoide metastásico en escolar de sexo masculino [Metastatic squamous cell carcinoma in a 12 year-old boy]. Dermatología Peruana (ISSN 1028-7175), 15(3):249-253.
Zambrano E, Mejía-Mejía O, Bifulco C, Shin J, Reyes-Múgica M. (2006) Extranodal marginal zone B-cell lymphoma/ maltoma of the lip in a child. Case report and review of cutaneous lymphoid proliferations in childhood. International Journal of Surgical Pathology, 14(2):163-169.
Stock F, Zambrano E, Cammarata-Scalisi F, Milano M, Petrosino P, Arenas A, Valderrama-Landaeta JL. (2008) Tumor desmoplástico de células redondas pequeñas. Reporte de un caso y revisión de la literatura [Desmoplastic small round cell tumor. A case report in a 13-year-old girl]. Revista Médica de la Extensión Portuguesa - ULA. 2(1):11-16.
Theoharis CGA, Carling T, Buza N, Zambrano E, Sosa JA. (2008) Multinodular Goiter and Primary Hyperparathyroidism: A Circuitous Route to Diagnosing Metastatic Uveal Melanoma. Endocrine Pathology, 19(4):294-8.
Moliterno JA, Sood S, Zambrano E, Kim JH, Piepmeier JM, Baehring JM. (2009) Intracranial Benign Fibrous Histiocytomas: A Case Report and Review. Journal of Neuro-Oncology J Neurooncol, 92(2):203-209.
Esquibies AE, Zambrano E, Ziai J, Kesebir D, Touloukian RJ, Egan ME , Reyes-Múgica M, Bazzy-Asaad A.(2010) Pulmonary Squamous Cell Carcinoma Associated with Repaired Congenital Tracheoesophageal Fistula and Esophageal Atresia. Pediatric Pulmonology, 45(2):202-4.
Ziai J, French CA, Zambrano E. NUT gene rearrangement in a poorly-differentiated carcinoma of the submandibular gland. Head and Neck Pathology. In press.
León-Ferré R, Friedlaender G, Vanegas T, Zambrano E. Post-radiation osteosarcoma in two young patients: Case reports and review of literature. In preparation.
Malhotra Y and Fitzgerald TN, Diefenbach KA, Harper H, Zambrano E, Cicero S, Moss RL, Bhandari V. A curious case of hemoperitoneum in a neonate: Case report and a review of rhabdoid tumors. In preparation.
Review Articles:
Ruiz JC, Zambrano EV, Ruiz EA. (1995) Análisis de asociación genética [Linkage analysis]. Revista Científica Medicina (ISSN 1390-0218), 1, No.3, 104- 109.
Zambrano EV. (1996) Biología molecular del cáncer [Molecular biology of cancer]. Oncología (ISSN 1390-0110), 6, No. 2, 181-188.
Zambrano-Tola E. (1996) Mecanismos moleculares de activación oncogénica [Molecular mechanisms of oncogenic activation]. Oncología (ISSN 1390-0110), 6(4):390-6.
Zambrano-Tola E, Merino-Espinoza M. (1997) Técnicas de diagnóstico molecular [Molecular diagnostic techniques]. Oncología (ISSN 1390-0110), 7(2):137-42.
Camelo-Piragua SI, Zambrano E, Pantanowitz L. Langerhans cell histiocytosis. Ear, Nose and Throat Journal (in press).
Original Papers:
Zambrano EV, Cuppens H, Legius E, Ruiz JC, Cassiman JJ. (1996) Caracterización de mutaciones en el gen de la adenilosuccinato liasa (ASL) en un paciente con epilepsia, retardo psicomotor y autismo [Characterization of mutations in the adenylosuccinate lyase gene (ASL) in a patient with epilepsy, psychomotor retardation and autism]. Revista Científica Medicina (ISSN 1390-0218), 2, No. 2, 99-104.
Zambrano-Tola E, Merino-Espinoza M. (1996) Estudio defamilias (pedigree) de pacientes con hemofilia A, fibrosis quística y síndrome del cromosoma X frágil, identificados en hospitales de la ciudad de Guayaquil [Family studies (pedigree) of patients with hemophilia A, cystic fibrosis and fragile X syndrome, identified from hospitals in the city of Guayaquil]. Revista de Investigación de laUniversidad Católica de Santiago de Guayaquil, 9, 7-30.
Marie E, Cuppens H, Heuterspreute M, Jaspers M, Zambrano-Tola E, Gu XX, Legius E, Vincent MF, Jaeken J, Cassiman JJ, Van den Berghe G. (1999) Mutation analysis in adenylosuccinate lyase deficiency: eight novel mutations in the re-evaluated full ADSL coding sequence. Human Mutation. 13: 197-202.
Zambrano E, Reyes-Múgica M. (2002) Hormonal activity may predict aggressive behavior in neuroblastoma. Pediatric and Developmental Pathology. 5 (2): 190-199.
Zambrano E, Reyes-Múgica M, Franchi A, Rosai J. (2003) An osteoclast-rich tumor of the gastrointesinal tract with features resembling clear cell sarcoma of soft parts: reports of six cases of a GIST simulator. International Journal of Surgical Pathology. 11(2):75-81.
Zambrano E, Holm I, Glickman J, Huang S, Perez-Atayde A, Kozakewich HPW, Shamberger RC, Nosé V. (2004) Abnormal distribution and hyperplasia of thyroid C-cells in PTEN-associated tumor syndromes. Endocrine Pathology. 15(1):55-64.
Zambrano E, Nose V, Richkind K, Gebhardt M, Hresko M, Kleinman P, Perez-Atayde A, Kozakewich H. (2004) Distinct chromosomal rearrangements in Dupuytren’s exostosis and Nora’s lesion. American Journal of Surgical Pathology. 28(8): 1033-1039.
Zambrano E, El-Hennawy M, Ehrenkranz R, Reyes-Múgica M. (2004) Total parenteral nutrition (TPN)-induced liver pathology. An autopsy series of 24 newborn cases. Pediatric and Developmental Pathology. 7(5): 425-432.
Zambrano E, Pérez-Atayde A, Ahrens W, Reyes-Múgica M. (2006) Pediatric Sclerosing Rhabdomyosarcoma. International Journal of Surgical Pathology. 14(3): 193-197.
Cajaiba MM, Sarita-Reyes C, Zambrano E, Miguel Reyes-Múgica. (2007) Mesenchymal Hamartoma of the Liver Associated with Beckwith-Wiedemann Syndrome Features and High Serum Alphafetoprotein Levels. Pediatric and Developmental Pathology. 10(3): 233-238.
Kenney B, Richkind KE, Zambrano E. (2007) Solid Variant of Aneurysmal Bone Cyst with a Novel (X;9) Translocation. Cancer Genetics and Cytogenetics. 178(2):155-159.
Hecht JL, Kliman HJ, Allred EN, Pflueger SMV, Chang CH, Doss B, Roberts D, Livasy C, Bhan I, Zambrano E, Ross DW, Senagore P, Husain A, Leviton A. (2007) Reference weights for placentas delivered before the 28th week of gestation. Placenta. 28(10):987-990.
Kenney B, Richkind KE, Friedlaender G, Zambrano E. (2007)Chromosomal Rearrangements In Lipofibromatosis. Cancer Genetics and Cytogenetics. 179:136-139.
Kim J, Zambrano E, McNiff JM. (2007) Congenital Panfollicular Nevus Associated with Polydactyly. Journal of Cutaneous Pathology. 34 (Suppl. 1):14-17.
De Stefano D, Peining L, Xiang B, Hui P, Zambrano E. (2008) Pulmonary atresia with intact ventricular septum (PA-IVS) in monozygotic twins. Am J Med Genet A.146A(4):525-528.
Buhimschi IA, Zambrano E, Pettker CM, Bahtiyar MO, Paidas M, Rosenberg VA, Thung S, Salafia CM, Buhimschi CS. (2008) Using proteomic analysis of the human amniotic fluid to identify histological chorioamnionitis. Obstet Gynecol. 111(2):403-412.
Hecht JL, Onderdonk A, Delaney M, Allred EN, Kliman HJ, Zambrano E, Solveig P, Livasy C, Bhan I, Leviton A. (2008) Characterization of chorioamnionitis in second trimester c-section placentas and correlation with microorganism recovery from sub-amniotic tissues. Pediatr Dev Pathol. 11(1):15-22.
Gathungu GN, Pashankar DS, Sarita-Reyes CD, Zambrano E, Reyes-Mugica M, Brueckner M, Mistry PK, Husain SZ. (2008) Microvillus Inclusion Disease Associated With Coarctation of the Aorta and Bicuspid Aortic Valve. J Clin Gastroenterol. 42(4):400-403.
Hecht JL, Allred EN, Kliman HJ, Zambrano E, Doss B, Husain A, Pflueger SMV, Chang C, Livasy C, Roberts D, Bhan I, Ross DW, Senagore PK, Leviton A. (2008) Histologic characteristics of placentas delivered before the 28th week of gestation. Pathology, 40(4):372-376.
Buhimschi CS, Abdel-Razeq S,Cackovik M, Pettker CM, Dulay AT, Mert-Ozan B, Zambrano E, Martin R, Norwitz ER,Bhandari V, Buhimschi IA. (2008) FHR monitoring patterns in women with amniotic fluid proteomic profiles indicative of inflammation. American Journal of Perinatology, 25(6):359-372.
Guller S, Buhimschi CS, Ma YY, Huang STJ, Yang L, Kuczynski E, ZambranoE, LockwoodCJ, Buhimschi IA. (2008) Placental Expression of Ceruloplasmin in Pregnancies with Severe Preeclampsia. Laboratory Investigation, 88:1057–1067.
McElrath TF, Hecht JL, Dammann O, Boggess K, Onderdonk A, Markenson G, Harper M, Delpapa E, Allred EN, Leviton A; ELGAN Study Investigators. (2008) Pregnancy disorders that lead to delivery before the 28th week of gestation: an epidemiologic approach to classification. Am J Epidemiol, 168(9):980-989.
Onderdonk AB, Hecht JL, McElrath TF, Delaney ML, Allred EN, Leviton A; ELGAN Study Investigators. (2008) Colonization of second-trimester placenta parenchyma. Am J Obstet Gynecol, 199(1):52.e1-52.e10.
McElrath TF, Allred EN, Boggess KA, Kuban K, O'Shea TM, Paneth N, Leviton A; ELGAN Study Investigators. (2009) Maternal antenatal complications and the risk of neonatal cerebral white matter damage and later cerebral palsy in children born at an extremely low gestational age. Am J Epidemiol, 170(7):819-828.
Book Chapters:
Astudillo-De la Vega H, Zambrano E. (2008) “New Strategies in the Diagnosis and Treatment of Cancer”, In: Molecular Biology of Cancer, Clínicas Oncológicas de Iberoamérica Series, México DF, México, 264 pp.
León-Ferré R, Areán-Cuns C, Zambrano E. (2009) “Cytogenetic and Molecular Aspects of Bone and Soft Tissue Neoplasms”, In: Avances en Patología, 5th ed, Ed. Cabildo de Fuerteventura, Spain.
León-Ferré R, Areán-Cuns C, Zambrano E. (2009) “Genetic Syndromes Associated with Sarcomas”, In: Avances en Patología, 5th ed, Ed. Cabildo de Fuerteventura, Spain.
Textbooks:
Zambrano-Tola, Eduardo (1996) Introducción a la Biología Molecular [Introduction to Molecular Biology], 1st ed., Editorial Universitaria - Universidad Católica de Santiago de Guayaquil (UCSG), Guayaquil, Ecuador.